Medication for Anxiety and Depression: These may be a good choice for those experiencing both anxiety and depression. However, sometimes higher doses can be overstimulating and contribute to anxiety. This may be less likely with citalopram and escitalopram. Sometimes even low doses can trigger anxiety in certain people. I know it sounds paradoxical that the medicine being used to help anxiety can trigger it instead. This at least partially reflects many issues including the fact that while we have come a long way in psychiatry with psychotropic medicines, we still have a long way to go. The prescribing of anxiety meds is not an exact science at all.