Lortab 7.5-325 mg is a prescription drug that treats moderate to severe pain. Hydrocodone, an opioid pain reliever, is combined with acetaminophen, a non-opioid pain reliever. Lortab comes in tablet form and is taken every 4-6 hours as needed to relieve pain. If you are interested in taking Lortab, it would be important to talk to your healthcare provider to decide if Lortab is the best medication for you and discuss any risks or benefits.Avoid alcohol while taking Lortab as it may increase the risk of side effects.