Mesothelioma - What Causes mesothelioma lawyer Other Than Asbestos? Asbestos is the sole cause of mesothelioma. It can cause damage to the lung linings, abdomen (peritoneal mesothelioma), and heart (pericardial mesothelioma). Other risk factors are radiation therapy for cancer, genetics, and minerals that are similar to asbestos, such as silica and Erionite....