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CRISPR/Cas9 technology is rapidly evolving in an unprecedented way in the field of gene editing, with its core components: gRNA and Cas9 endonuclease. Cas9 targets the specific sequence in the genome under gRNA guidance and cleaves the DNA duplex at the target site to form a DSB nick. This, in turn, triggers DNA repair mechanisms: non-homologous end-linking ...
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Creative Bioarray has experience in conducting single or repeated dose radiolabeled tissue distribution studies using tissue dissection or quantitative whole-body autoradiography (QWBA) methods to meet the sensitivity and specificity required for a comprehensive ADME program.
