CRISPR/Cas9 technology is rapidly evolving in an unprecedented way in the field of gene editing, with its core components: gRNA and Cas9 endonuclease. Cas9 targets the specific sequence in the genome under gRNA guidance and cleaves the DNA duplex at the target site to form a DSB nick. This, in turn, triggers DNA repair mechanisms: non-homologous end-linking ...
CRISPR/Cas9 PlatformCB is dedicated to providing professional CRISPR/Cas9 gene editing services and products for biotechnology, biomedical research, and pharmaceutical research. We provide you with custom HDR vectors service from strategic design to final stable and efficient HDR vectors, and keep in touch with you to report on project progress.
CRISPR/Cas9 PlatformCB offers a base editing service with trusted results and affordable price. Once you place an order, our skilled staff will work for your project with excellent platform under the supervision of experienced scientists.
CRISPR/Cas9 Platform provides a series of sgRNA service, including sequence design, synthesis, validation of efficiency and off-target analysis. In the past decade, our talented scientists are focusing on the development of gene-editing technology and are following the latest technique in this field. Our staff is experienced in sgRNA design and efficiency an...
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Creative Bioarray has experience in conducting single or repeated dose radiolabeled tissue distribution studies using tissue dissection or quantitative whole-body autoradiography (QWBA) methods to meet the sensitivity and specificity required for a comprehensive ADME program.
Bioavailability and bioequivalence studies play an important role in the development of both new drugs and their generic equivalents. There are several approaches to assess BE, and each regulatory authority has its own regulations for conducting BA/BE research. At Creative Bioarray, our scientists fully understand the specifications and requirements of each ...
Creative Bioarray develops and performs rapid, sensitive and robust bioanalytical methods for the extraction and quantitation of drugs and metabolites in biological fluids and tissues to support preclinical research. We provide cost-effective design and implementation of in vivo pharmacokinetic studies in various animal species and quick turnaround of result...
Pharmacodynamics (PD) refers to the action of a drug to the body, involving receptor binding, post-receptor effects, and chemical interactions. Pharmacokinetics (PK) determines the onset, duration, and intensity of drug action. Successful drug discovery relies on the selection of drug candidates with good in vivo PK properties, as well as appropriate preclin...
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