How much weight can you lose in a month with Wegovy? The active ingredient in Ozempic and Wegovy is the same, and the early dosing schedules are also the same, so the earlier rate of weight loss is very similar. On Ozempic and Wegovy, you can expect to lose up to 5% of your weight in the first month on Wegovy and up to 8% after two months. Please take note o...