Wartrol is clinically proven and uses FDA-approved ingredients to remove common warts and plantar warts caused by HPV. Wartrol is a fast-acting, painless liquid that is available in a convenient drop applicator. Warts are caused by the Human Papilloma Virus (HPV), which enters your body through small cuts, cracks, or other vulnerable parts of the skin. These warts often appear on pressure points and can be painful and unsightly.