Fioricet is a prescription medication primarily used for the treatment of tension headaches. Fioricet is FDA-approved for the relief of tension headaches, which are characterized by a dull, aching head pain, often accompanied by muscle tension in the neck and shoulders. Butalbital, one of the active ingredients in Fioricet, acts as a muscle relaxant and sedative, helping to relieve muscle tension and promote relaxation. Fioricet is primarily indicated for tension headaches, it may also be used off-label for the management of migraines in some cases.