Since the dawn of civilization, worst calamities have been a part of life on Earth, but the death tolls from the oldest of these worst calamities have been lost to history. According to a 2020 study published in the journal Proceedings of the National Academies of Sciences, the Minoan civilization was completely wiped out around 1600 B.C. on the ancient Mediterranean island of Thera (currently Santorini, Greece). But precisely how many people perished? The answer is unknown.